Pathobiology Course for Research Scientists: Resolution of Inflammation

Pathobiology Course for Research Scientists: Resolution of Inflammation

Sunday, April 5, 2020 • 2:00 PM - 5:00 PM

SDCC, Room 5A

Sponsored by the ASIP Education Committee

Chair: Dipak Panigrahy, MD • Beth Israel Deaconess Medical Center/Harvard Medical School
Co-Chair: Alexander Sougiannis, BS, MA • University of South Carolina School of Medicine

Session Description: Unresolved inflammation is a major mechanism of pathogenesis in many human diseases. A paradigm shift is emerging in our understanding of the pathogenesis of inflammation which results not only from persistent activation of inflammatory signals, but also from the active loss of pro-resolution mechanisms. Differentiating between the suppression and resolution of inflammation driven by pro-resolution mediators is critical for the treatment of various inflammatory diseases.

  • Chair - Welcome and Introductions
  • 2:00 PM - 2:45 PM
    Resolvins and Novel Pro-Resolving Mediators (SPM) are Immunoresolvent Agonists
    Charles N. Serhan, PhD • Brigham and Women's Hospital/Harvard Medical School
  • 2:45 PM - 3:30 PM
    Protein Sulfhydration in Inflammation and the Resolution of Inflammation
    Ingrid Fleming, PhD • Goethe University, Institute for Vascular Signaling, Germany
  • 3:30 PM - 4:15 PM
    Investigating the Formation of Eicosanoids and Other Oxylipins By Means of LC-MS
    Nils Helge Schebb, PhD • University of Wuppertal, Germany
  • 4:15 PM - 5:00 PM
    Epoxides of Fatty Acids and Soluble Epoxide Hydrolase InhibitorsResolve Inflammation and Block Senescence
    Bruce D. Hammock, PhD • University of California, Davis
  • Questions and Answers