Symposium: Novel Regulators and Functions of Epithelial Junctions

Symposium: Novel Regulators and Functions of Epithelial Junctions

Sunday, April 5, 2020 • 2:00 PM - 5:00 PM

SDCC, Room 4

Chair: Asma Nursat, MD • University of Michigan
Co-Chair: William Muller, MD, PhD • Northwestern University

Session Description: Epithelial junctions are key regulators of tissue integrity and homeostasis, and their compromise contributes to the pathogenesis of inflammatory and immune disorders. This symposium will highlight recent developments in this exciting area of research and will touch upon developmental and disease pathways. The talks will cover the role of intercellular junction proteins in a range of tissues, including simple and complex epithelia.

  • Chair - Welcome and Introductions
  • 2:00 PM - 2:45 PM
    How Desmosomal Cadherins Help to Create Complex Epithelia
    Kathleen Green, PhD • Northwestern University
  • 2:45 PM - 3:30 PM
    Regulation of Simple Epithelial Wound Repair by Desmosomal Cadherin, Desmocollin 2
    Asma Nusrat, MD • University of Michigan
  • 3:30 PM - 4:15 PM
    Actin and Myosin-Dependent Regulation of Epithelial Apical Junctions: How Many Skeletons are in the Closet?
    Andrei I. Ivanov, PhD • Lerner Research Institute of Cleveland Clinic Foundation
  • 4:15 PM - 5:00 PM
    Going In Circles Gets You Somewhere: Signaling Mechanisms That Coordinate Cell Movements For Epithelial Migration
    Sally Horne-Badovinac, PhD • The University of Chicago
  • Questions and Answers